CBPA4 Polyclonal Antibody
Ucallm_WP0978-50
Price range: $268.00 through $328.00
Product details
Background:
This gene is a member of the carboxypeptidase A/B subfamily, and it is located in a cluster with three other family members on chromosome 7. Carboxypeptidases are zinc-containing exopeptidases that catalyze the release of carboxy-terminal amino acids, and are synthesized as zymogens that are activated by proteolytic cleavage. This gene could be involved in the histone hyperacetylation pathway. It is imprinted and may be a strong candidate gene for prostate cancer aggressiveness. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | CBPA4 |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 46kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | CBPA4 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | CPA4 CPA3 UNQ694/PRO1339 |
| Protein Name | Carboxypeptidase A4 (Carboxypeptidase A3) |
| Other Name | |
| Species | Human |
| Gene ID | 51200 |
| Uniprot | Q9UI42, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q6P8K8 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Secreted . |
| Tissue Expression | Fetal expression in the adrenal gland, brain, heart, intestine, kidney, liver and lung. Except for fetal brain that shows no imprinting, expression was found preferentially from the maternal allele. |
| Signaling_pathway | |
| Research Areas | |
| Function | cofactor:Binds 1 zinc ion per subunit.,Function:Metalloprotease that could be involved in the histone hyperacetylation pathway.,induction:Up-regulated by inhibitors of histone dacetylation.,similarity:Belongs to the peptidase M14 family.,subunit:Interacts with LXN.,tissue specificity:Fetal expression in the adrenal gland, brain, heart, intestine, kidney, liver and lung. Except for fetal brain that shows no imprinting, expression was found preferentially from the maternal allele., |
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