Product details
Background:
- Please choose product options by visiting CC071 rabbit pAb.
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CBX7 rabbit pAb
Ucallm_WP6500-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | CBX7 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 28kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human CBX7 |
| Specificity | This antibody detects endogenous levels of CBX7 at Human, Mouse,Rat |
| Gene Name | CBX7 |
| Protein Name | Chromobox protein homolog 7 |
| Other Name | |
| Species | Human |
| Gene ID | 23492 |
| Uniprot | O95931, |
| Species.1 | Mouse |
| Gene ID.1 | 52609 |
| Uniprot.1 | Q8VDS3, |
| Species.2 | Rat |
| Gene ID.2 | 362962 |
| Uniprot.2 | P60889 |
| Cellular Localization | Nucleus . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to trimethylated lysine residues in histones, and possibly also other proteins. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity. |
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