Product details
Background:
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CCDC109B rabbit pAb
Ucallm_WP7268-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | MCUB |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 37kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human CCDC109B |
| Specificity | This antibody detects endogenous levels of CCDC109B at Human, Mouse |
| Gene Name | CCDC109B |
| Protein Name | Coiled-coil domain-containing protein 109B |
| Other Name | |
| Species | Human |
| Gene ID | 55013 |
| Uniprot | Q9NWR8, |
| Species.1 | Mouse |
| Gene ID.1 | 66815 |
| Uniprot.1 | Q810S1 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Mitochondrion inner membrane; Multi-pass membrane protein . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Negatively regulates the activity of MCU, the mitochondrial inner membrane calcium uniporter, and thereby modulates calcium uptake into the mitochondrion. Does not form functional calcium channels by itself. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways. |
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