Price range: $699.00 through $799.00
Background:
The protein encoded byThis gene is identical to adenosine deaminase complexing protein-2, and to the T-cell activation antigen CD26. It is an intrinsic membrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. [provided by RefSeq, Jul 2008]
| Target | CD26 |
| Reactivity | Human |
| Applications | ELISA |
| MW(Calculated) | |
| MW(Observed) | |
| Host Species | |
| Isotype | |
| Conjugate | |
| Modification | Unmodified |
| Recommended Dilution Ratio | ELISA 1:5000-100000 |
| Composition | Phosphate-buffered solution |
| Source | Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell |
| Purification Process | Recombinant Expression and Affinity purified |
| Purity | |
| Storage Condition | -15°C to -25°C/1 year(Avoid freeze / thaw cycles) |
| Concentration | Please check the information on the tube |
| Clonality | Monoclonal |
| Clone Number | PN0217 |
| Immunogen | Purified recombinant Human CD26 |
| Sequence | |
| Specificity | This recombinant monoclonal antibody can detects endogenous levels of CD26 protein. |
| Gene Name | DPP4 ADCP2 CD26 |
| Protein Name | Dipeptidyl peptidase 4 (ADABP) (Adenosine deaminase complexing protein 2) (ADCP-2) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (TP103) (CD antigen CD26) [Cleaved into: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)] |
| Alias | DPP4;ADCP2;CD26;Dipeptidyl peptidase 4;ADABP;Adenosine deaminase complexing protein 2;ADCP-2;Dipeptidyl peptidase IV;DPP IV;T-cell activation antigen CD26;TP103;CD26;CD26 nanobody; |
| Organism-1 | Human |
| Gene ID-1 | 1803.0 |
| SwissProt-1 | P27487 |
| Organism-2 | |
| Gene ID-2 | |
| SwissProt-2 | |
| Organism-3 | |
| Gene ID-3 | |
| SwissProt-3 | |
| Organism-4 | |
| Gene ID-4 | |
| SwissProt-4 | |
| Cellular Localization | [Dipeptidyl peptidase 4 soluble form]: Secreted . Detected in the serum and the seminal fluid. .; Cell membrane ; Single-pass type II membrane protein. Apical cell membrane ; Single-pass type II membrane protein. Cell projection, invadopodium membrane ; Single-pass type II membrane protein. Cell projection, lamellipodium membrane ; Single-pass type II membrane protein. Cell junction . Membrane raft . Translocated to the apical membrane through the concerted action of N- and O-Glycans and its association with lipid microdomains containing cholesterol and sphingolipids (PubMed:11773049). Redistributed to membrane rafts in T-cell in an interleukin-12-dependent activation (PubMed:12676959). Its interaction with CAV1 is necessary for its translocation to membrane rafts (PubMed:17287217). Colocalized with PTPRC in membrane rafts (PubMed:12676959). Colocalized with FAP in invadopodia and lamellipodia of migratory activated endothelial cells in collagenous matrix. Colocalized with FAP on endothelial cells of capillary-like microvessels but not large vessels within invasive breast ductal carcinoma (PubMed:16651416). Colocalized with ADA at the cell junction in lymphocyte-epithelial cell adhesion (PubMed:11772392). Colocalized with IGF2R in internalized cytoplasmic vesicles adjacent to the cell surface (PubMed:10900005). . |
