Product details
Background:
The protein encoded byThis gene is a member of the TNF-receptor superfamily.This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response.This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation.This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008]
