CD27 [PTR1377] recombinant mouse mAb
Ucallm_WM1327-50
Price range: $268.00 through $328.00
Product details
Background:
CD27 molecule(CD27) Homo sapiens The protein encoded byThis gene is a member of the TNF-receptor superfamily.This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis.This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process ofThis receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind toThis receptor and is thought to play an important role in the apoptosis induced byThis receptor. [provided by RefSeq, Jul 2008]
Specifications
| Size | 50μL/100μL |
| Target | CD38 |
| Reactivity | Human |
| Applications | FC, ELISA |
| MW(Calculated) | |
| MW(Observed) | |
| Host Species | Mouse |
| Isotype | IgG2a,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | ELISA 1:5000-100000; Flow Cyt 1-2μg/Test |
| Formulation | Phosphate-buffered solution |
| Purification | Recombinant Expression and Affinity purified |
| Storage | -15°C to -25°C/1 year(Avoid freeze / thaw cycles) |
| Concentration | Please check the information on the tube |
| Clonality | Monoclonal |
| Clone Number | RMMR1382 |
| Immunogen | Purified recombinant Human CD27 |
| Specificity | This recombinant monoclonal antibody can detects endogenous levels of CD27 protein. |
| Gene Name | CD27 TNFRSF7 |
| Protein Name | CD27 antigen (CD27L receptor) (T-cell activation antigen CD27) (T14) (Tumor necrosis factor receptor superfamily member 7) (CD antigen CD27) |
| Other Name | CD 27 antibody; / CD27 antibody; / CD27 antigen antibody; / CD27 molecule antibody; / CD27_HUMAN antibody; / CD27L receptor antibody; / LPFS2 antibody; / MGC20393 antibody; / OTTHUMP00000238557 antibody; / S152 antibody; / T cell activation antigen CD27 antibody; / T cell antivation antigen S152 antibody; / T-cell activation antigen CD27 antibody; / T14 antibody; / TNFRSF 7 antibody; / TNFRSF7 antibody; / TNFSF7 antibody; / Tp 55 antibody; / Tp55 antibody; / Tumor necrosis factor receptor superfamily member 7 antibody; / CD27 nanobody |
| Species | Human |
| Gene ID | 952 |
| Uniprot | P26842 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Membrane; Single-pass type I membrane protein. |
| Tissue Expression | Expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. |
| Signaling_pathway | Organismal Systems >> Immune system >> Hematopoietic cell lineage;Organismal Systems >> Endocrine system >> Oxytocin signaling pathway;Environmental Information Processing >> Signal transduction >> Calcium signaling pathway |
| Research Areas | |
| Function | Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1. |
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