Name: CD32-A Polyclonal Antibody
SKU: WP11499
Price: 268 USD
Availability: InStock

CD32-A Polyclonal Antibody

Ucallm_WP11499-50

Price range: $268.00 through $328.00

Size

100μl

50μl

Clear

SKU: WP11499-100

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Product details

Background:

Fc fragment of IgG receptor IIa(FCGR2A) Homo sapiens This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008],

Specifications

Size	50μL/100μL
Target	CD32
Reactivity	Human
Applications	WB, ELISA
MW(Calculated)
MW(Observed)	35kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	The antiserum was produced against synthesized peptide derived from human FCGR2A. AA range:241-290
Specificity	CD32-A Polyclonal Antibody detects endogenous levels of CD32-A protein.
Gene Name	FCGR2A
Protein Name	Low affinity immunoglobulin gamma Fc region receptor II-a
Other Name	FCGR2A; / CD32; / FCG2; / FCGR2A1; / IGFR2; / Low affinity immunoglobulin gamma Fc region receptor II-a; / IgG Fc receptor II-a; / CDw32; / Fc-gamma RII-a; / Fc-gamma-RIIa; / FcRII-a; / CD antigen CD32
Species	Human
Gene ID	2212
Uniprot	P12318
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	Cell membrane; Single-pass type I membrane protein .
Tissue Expression	Found on monocytes, neutrophils and eosinophil platelets.
Signaling_pathway	Cellular Processes >> Transport and catabolism >> Phagosome;Organismal Systems >> Immune system >> Platelet activation;Organismal Systems >> Immune system >> Neutrophil extracellular trap formation;Organismal Systems >> Immune system >> Fc gamma R-mediated phagocytosis;Organismal Systems >> Development and regeneration >> Osteoclast differentiation;Human Diseases >> Immune disease >> Systemic lupus erythematosus
Research Areas	>>Phagosome; / >>Osteoclast differentiation; / >>Platelet activation; / >>Neutrophil extracellular trap formation; / >>Fc gamma R-mediated phagocytosis; / >>Pathogenic Escherichia coli infection; / >>Yersinia infection; / >>Leishmaniasis; / >>Staphylococcus aureus infection; / >>Tuberculosis; / >>Coronavirus disease - COVID-19; / >>Systemic lupus erythematosus
Function	Function:Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Interacts with INPP5D/SHIP1 and INPPL1/SHIP2, regulating its function.,tissue specificity:Found on monocytes, neutrophils and eosinophil platelets.,

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CD32-A Polyclonal Antibody

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CD32-A Polyclonal Antibody

Product details

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