CD56 [ABT500] mouse mAb
Product details
Background:
This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. The encoded protein has been shown to be involved in development of the nervous system, and for cells involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011],
Specifications
| Size | 50μL/100μL |
| Target | CD56 |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC, WB, IF, ELISA |
| MW(Calculated) | 95kD |
| MW(Observed) | 100kD |
| Host Species | Mouse |
| Isotype | IgG1,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:200-1000; WB 1:500-2000; IF 1:100-500; ELISA 1:1000-5000 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein G affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RMM500 |
| Immunogen | Synthesized peptide derived from human CD56 AA range: 500-600 |
| Specificity | The antibody can specifically recognize human CD56 protein. |
| Gene Name | NCAM1 NCAM |
| Protein Name | antigen MSK39 identified by monoclonal 5.1H11; antigen recognized by monoclonal 5.1H11; CD56; cell adhesion molecule, neural, 1; MSK 39; MSK39; N-CAM-1; NCAM 1; NCAM; NCAM C; NCAM-1; NCAM1; NCAM1_HUMAN; NCAMC; Neural cell adhesion molecule 1; Neural cell adhesion molecule NCAM; OTTHUMP00000235666 |
| Other Name | antigen MSK39 identified by monoclonal 5.1H11; / antigen recognized by monoclonal 5.1H11; / CD56; / cell adhesion molecule, neural, 1; / MSK 39; / MSK39; / N-CAM-1; / NCAM 1; / NCAM; / NCAM C; / NCAM-1; / NCAM1; / NCAM1_HUMAN; / NCAMC; / Neural cell adhesion molecule 1; / Neural cell adhesion molecule NCAM; / OTTHUMP00000235666 |
| Species | Human |
| Gene ID | 4684 |
| Uniprot | P13591, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P13595, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | P13596 |
| Cellular Localization | Membranous, Cytoplasmic |
| Tissue Expression | Tonsil/ Appendix |
| Signaling_pathway | Human Diseases >> Neurodegenerative disease >> Prion disease;Environmental Information Processing >> Signaling molecules and interaction >> Cell adhesion molecules |
| Research Areas | >>Cell adhesion molecules; / >>Prion disease |
| Function | Function:This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.,online information:N-CAM 140,online information:NCAM entry,similarity:Contains 2 fibronectin type-III domains.,similarity:Contains 5 Ig-like C2-type (immunoglobulin-like) domains., |
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