SKU: WP15692 Categories: ,

CD56 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP15692-100
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Product details

Background:

This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. The encoded protein has been shown to be involved in development of the nervous system, and for cells involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011],

Specifications

Size50μL/100μL
TargetCD56
ReactivityHuman
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)94kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioIHC 1:200-1:1000; WB 1:500-1:2000; ELISA 1:10000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human NCAM1. AA range:250-300
SpecificityCD56 Polyclonal Antibody detects endogenous levels of CD56 protein.
Gene NameNCAM1
Protein NameNeural cell adhesion molecule 1
Other NameNCAM1; / NCAM; / Neural cell adhesion molecule 1; / N-CAM-1; / NCAM-1; / CD56
SpeciesHuman
Gene ID4684
UniprotP13591,
Species.1Mouse
Gene ID.1
Uniprot.1P13595
Species.2
Gene ID.2
Uniprot.2
Cellular Localization[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Cell membrane; Single-pass type I membrane protein.; [Isoform 3]: Cell membrane; Lipid-anchor, GPI-anchor.; [Isoform 4]: Cell membrane; Lipid-anchor, GPI-anchor .; [Isoform 5]: Secreted.; [Isoform 6]: Secreted .
Tissue ExpressionBrain,Brain cortex,Kidney,Ovary,Plasma,Skeletal muscle,Testis,
Signaling_pathwayHuman Diseases >> Neurodegenerative disease >> Prion disease;Environmental Information Processing >> Signaling molecules and interaction >> Cell adhesion molecules
Research Areas>>Cell adhesion molecules; / >>Prion disease
FunctionFunction:This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.,online information:N-CAM 140,online information:NCAM entry,similarity:Contains 2 fibronectin type-III domains.,similarity:Contains 5 Ig-like C2-type (immunoglobulin-like) domains.,
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