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CD56 Polyclonal Antibody
Ucallm_WP15692-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. The encoded protein has been shown to be involved in development of the nervous system, and for cells involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011],
Specifications
| Size | 50μL/100μL |
| Target | CD56 |
| Reactivity | Human |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 94kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:200-1:1000; WB 1:500-1:2000; ELISA 1:10000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human NCAM1. AA range:250-300 |
| Specificity | CD56 Polyclonal Antibody detects endogenous levels of CD56 protein. |
| Gene Name | NCAM1 |
| Protein Name | Neural cell adhesion molecule 1 |
| Other Name | NCAM1; / NCAM; / Neural cell adhesion molecule 1; / N-CAM-1; / NCAM-1; / CD56 |
| Species | Human |
| Gene ID | 4684 |
| Uniprot | P13591, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P13595 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Cell membrane; Single-pass type I membrane protein.; [Isoform 3]: Cell membrane; Lipid-anchor, GPI-anchor.; [Isoform 4]: Cell membrane; Lipid-anchor, GPI-anchor .; [Isoform 5]: Secreted.; [Isoform 6]: Secreted . |
| Tissue Expression | Brain,Brain cortex,Kidney,Ovary,Plasma,Skeletal muscle,Testis, |
| Signaling_pathway | Human Diseases >> Neurodegenerative disease >> Prion disease;Environmental Information Processing >> Signaling molecules and interaction >> Cell adhesion molecules |
| Research Areas | >>Cell adhesion molecules; / >>Prion disease |
| Function | Function:This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.,online information:N-CAM 140,online information:NCAM entry,similarity:Contains 2 fibronectin type-III domains.,similarity:Contains 5 Ig-like C2-type (immunoglobulin-like) domains., |
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