SKU: WM1379 Categories: ,

CD9 [PTR1357] mouse mAb

Price range: $268.00 through $328.00

SKU: WM1379-50
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Product details

Background:
This gene encodes a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Tetraspanins are cell surface glycoproteins with four transmembrane domains that form multimeric complexes with other cell surface proteins. The encoded protein functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression of this gene plays a critical role in the suppression of cancer cell motility and metastasis. [provided by RefSeq, Jan 2011],

Specifications

Size50μL/100μL
TargetCD9
ReactivityHuman
ApplicationsWB, IF, ELISA
MW(Calculated)24kD
MW(Observed)22kD
Host SpeciesMouse
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; IF 1:100-500; ELISA 1:1000-5000
FormulationPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
PurificationRecombinant Antibody expressed in animal component-free (ACF) media, purified via Protein G affinity chromatography.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
ClonalityMonoclonal
Clone NumberRMMR1357
ImmunogenThe antiserum was produced against synthesized peptide derived from human CD9. AA range:100-200
SpecificityThis antibody detects endogenous levels of CD9.
Gene NameCD9
Protein NameCD9 antigen
Other NameCD9; / MIC3; / TSPAN29; / GIG2; / CD9 antigen; / 5H9 antigen; / Cell growth-inhibiting gene 2 protein; / Leukocyte antigen MIC3; / Motility-related protein; / MRP-1; / Tetraspanin-29; / Tspan-29; / p24; / CD antigen CD9
SpeciesHuman
Gene ID928
UniprotP21926
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Tissue ExpressionDetected in platelets (at protein level) (PubMed:19640571). Expressed by a variety of hematopoietic and epithelial cells (PubMed:19640571).
Signaling_pathwayOrganismal Systems >> Immune system >> Hematopoietic cell lineage
Research Areas>>Hematopoietic cell lineage
FunctionFunction:Involved in platelet activation and aggregation. Regulates paranodal junction formation. Involved in cell adhesion, cell motility and tumor metastasis. Required for sperm-egg fusion.,PTM:Protein exists in three forms with molecular masses between 22 and 27 kDa, and is known to carry covalently linked fatty acids.,similarity:Belongs to the tetraspanin (TM4SF) family.,subunit:Forms both disulfide-linked homodimers and higher homooligomers as well as heterooligomers with other members of the tetraspanin family. Associates with CR2/CD21 and with PTGFRN/CD9P1. Interacts directly with IGSF8.,tissue specificity:Expressed by a variety of hematopoietic and epithelial cells.,
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