SKU: WM1396 Categories: ,

CD99 [ABT156] mouse mAb

Price range: $268.00 through $328.00

SKU: WM1396-50
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Product details

Background:
CD99 is a 32 kDa transmembrane glycoprotein which is thought to be involved in cell adhesion processes. CD99 was expressed in lymphocytes, thymic cortical cells, ovarian granulosa cells, islet cells, Sertoli cells of testis, immature terminal deoxynucleotidyl transferase (TDT) positive T cells, some bone marrow precursor cells and fibroblasts. At the same time, CD99 was also expressed in vascular endothelial cells, urethral epithelium, some columnar and squamous epithelial cells and ependymal cells. It is mainly used for the diagnosis of Ewing’s sarcoma and primitive peripheral nerve endodermal tumor.

Specifications

Size50μL/100μL
TargetCD99
ReactivityHuman
ApplicationsIHC, WB, IF, ELISA
MW(Calculated)19kD
MW(Observed)28kD
Host SpeciesMouse
IsotypeIgG1,Kappa
Conjugate/ModificationUnmodified
Recommended Dilution RatioIHC 1:200-1000; WB 1:500-2000; IF 1:100-500; ELISA 1:1000-5000 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
PurificationRecombinant Antibody expressed in animal component-free (ACF) media, purified via Protein G affinity chromatography.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
ClonalityMonoclonal
Clone NumberRMM156
ImmunogenSynthesized peptide derived from human CD99 AA range: 1-100
SpecificityThe antibody can specifically recognize human CD99 protein.
Gene NameCD99 MIC2 MIC2X MIC2Y
Protein NameCD99
Other Name12E7; / Antigen identified by monoclonal 12E7, Y homolog; / Antigen identified by monoclonal antibodies 12E7, F21 and O13; / CD99; / Cell surface antigen 12E7; / Cell surface antigen HBA 71; / Cell surface antigen O13; / E2 antigen; / HBA71; / MIC 2X; / MIC 2Y; / MIC2; / MIC2X; / MIC2Y; / MSK5X; / Protein MIC2; / Surface antigen MIC2; / T cell surface glycoprotein E2
SpeciesHuman
Gene ID4267
UniprotP14209
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationMembranous
Tissue ExpressionMembranous
Signaling_pathwayOrganismal Systems >> Immune system >> Leukocyte transendothelial migration;Environmental Information Processing >> Signaling molecules and interaction >> Cell adhesion molecules
Research Areas>>Cell adhesion molecules; / >>Leukocyte transendothelial migration
FunctionFunction:Involved in T-cell adhesion processes. It is involved in spontaneous rosette formation with erythrocytes.,miscellaneous:The gene encoding for this protein is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes.,PTM:Extensively O-glycosylated.,similarity:Belongs to the CD99 family.,
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