Price range: $268.00 through $328.00
Background:
CDC37L1 is a cytoplasmic phosphoprotein that exists in complex with HSP90 (HSPCA; MIM 140571) as well as several other proteins involved in HSP90-mediated protein folding (Scholz et al., 2001 [PubMed 11413142]).[supplied by OMIM, Mar 2008],
| Size | 50μL/100μL |
| Target | Cdc37L1 |
| Reactivity | Human, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 38kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; ELISA 1:40000; Not yet tested in other applications. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from Cdc37L1 . at AA range: 80-160 |
| Specificity | Cdc37L1 Polyclonal Antibody detects endogenous levels of Cdc37L1 protein. |
| Gene Name | CDC37L1 |
| Protein Name | Hsp90 co-chaperone Cdc37-like 1 |
| Other Name | CDC37L1; / CDC37B; / HARC; / Hsp90 co-chaperone Cdc37-like 1; / Hsp90-associating relative of Cdc37 |
| Species | Human |
| Gene ID | 55664 |
| Uniprot | Q7L3B6, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q9CZP7, |
| Species.2 | Rat |
| Gene ID.2 | 293886 |
| Uniprot.2 | Q5XIC3 |
| Cellular Localization | Cytoplasm . |
| Tissue Expression | Expressed in brain, heart, kidney, liver, placenta and skeletal muscle. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Co-chaperone that binds to numerous proteins and promotes their interaction with Hsp70 and Hsp90.,sequence Caution:Translated as Cys.,similarity:Belongs to the CDC37 family.,subunit:Self-associates. Forms complexes with Hsp70 and Hsp90. Interacts with CDC37, FKBP4, PPID and STIP1.,tissue specificity:Expressed in brain, heart, kidney, liver, placenta and skeletal muscle., |
