CEP135 Polyclonal Antibody
Product details
Background:
centrosomal protein 135(CEP135) Homo sapiens This gene encodes a centrosomal protein, which acts as a scaffolding protein during early centriole biogenesis, and is also required for centriole-centriole cohesion during interphase. Mutations in this gene are associated with autosomal recessive primary microcephaly-8. [provided by RefSeq, Jun 2012],
Specifications
| Size | 50μL/100μL |
| Target | CEP135 |
| Reactivity | Human, Mouse |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 134kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CEP135. AA range:1081-1130 |
| Specificity | CEP135 Polyclonal Antibody detects endogenous levels of CEP135 protein. |
| Gene Name | CEP135 |
| Protein Name | Centrosomal protein of 135 kDa |
| Other Name | CEP135; / CEP4; / KIAA0635; / Centrosomal protein of 135 kDa; / Cep135; / Centrosomal protein 4 |
| Species | Human |
| Gene ID | 9662 |
| Uniprot | Q66GS9, |
| Species.1 | Mouse |
| Gene ID.1 | 381644 |
| Uniprot.1 | Q6P5D4 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . During centriole biogenesis, it is concentrated within the proximal lumen of both parental centrioles and procentrioles. |
| Tissue Expression | Brain,Epithelium,Placenta, |
| Signaling_pathway | |
| Research Areas | |
| Function | similarity:Belongs to the CEP135/TSGA10 family., |
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