Price range: $268.00 through $328.00
Background:
This gene encodes a centrosomal and microtubule-binding protein which is predicted to have two coiled-coil domains and a rhodanese domain. In human retinal pigment epithelial cells the protein localized to centrioles and cilia. Mutations in this gene have been associated with Joubert Syndrome 15; an autosomal recessive ciliopathy and neurological disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012],
| Size | 50μL/100μL |
| Target | CEP41 |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 41kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CEP41. AA range:150-200 |
| Specificity | CEP41 Polyclonal Antibody detects endogenous levels of CEP41 protein. |
| Gene Name | CEP41 |
| Protein Name | Centrosomal protein of 41 kDa |
| Other Name | CEP41; / TSGA14; / Centrosomal protein of 41 kDa; / Cep41; / Testis-specific gene A14 protein |
| Species | Human |
| Gene ID | 95681 |
| Uniprot | Q9BYV8, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q99NF3 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Localizes mainly to the cilium basal body and in primary cilia. |
| Tissue Expression | [Isoform 1]: Expressed in testis and fetal tissues.; [Isoform 3]: Expressed in testis and fetal tissues. |
| Signaling_pathway | |
| Research Areas | |
| Function | similarity:Contains 1 rhodanese domain.,tissue specificity:Isoform 1 and isoform 4 are expressed in testis and fetal tissues., |
