SKU: WP11591 Categories: ,

Cep97 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP11591-100
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Product details

Background:

function:Collaborates with cep110, being involved in the suppression of a cilia assembly program. Required for correct spindle formation and has a role in cytokinesis. Required for recruitment of cep110 to the centrosome., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Contains 1 IQ domain., similarity:Contains 6 LRR (leucine-rich) repeats., subunit:Interacts with CALM1 and CEP110.,

Specifications

Size50μL/100μL
TargetCep97
ReactivityHuman, Mouse
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)97kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human CEP97. AA range:581-630
SpecificityCep97 Polyclonal Antibody detects endogenous levels of Cep97 protein.
Gene NameCEP97
Protein NameCentrosomal protein of 97 kDa
Other NameCEP97; / LRRIQ2; / Centrosomal protein of 97 kDa; / Cep97; / Leucine-rich repeat and IQ domain-containing protein 2
SpeciesHuman
Gene ID79598
UniprotQ8IW35,
Species.1Mouse
Gene ID.174201
Uniprot.1Q9CZ62
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Recruited at the distal end of the mother centriole by MPHOSPH9. .
Tissue ExpressionLung,Skin,Testis,
Signaling_pathway
Research Areas
FunctionFunction:Collaborates with cep110, being involved in the suppression of a cilia assembly program. Required for correct spindle formation and has a role in cytokinesis. Required for recruitment of cep110 to the centrosome.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 IQ domain.,similarity:Contains 6 LRR (leucine-rich) repeats.,subunit:Interacts with CALM1 and CEP110.,
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