Price range: $268.00 through $328.00
Background:
This gene encodes a member of a family of small secreted proteins containing C1Q domains. Members of this family are involved in regulation of neurexin signalling during synapse development. The mouse homolog of the protein encoded by this gene competes with netrin to bind to the deleted in colorectal cancer receptor. [provided by RefSeq, Aug 2012],
| Size | 50μL/100μL |
| Target | Cerebellin 4 |
| Reactivity | Human, Mouse, Monkey |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 27kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CBLN4. AA range:141-190 |
| Specificity | Cerebellin 4 Polyclonal Antibody detects endogenous levels of Cerebellin 4 protein. |
| Gene Name | CBLN4 |
| Protein Name | Cerebellin-4 |
| Other Name | CBLN4; / CBLNL1; / Cerebellin-4; / Cerebellin-like glycoprotein 1 |
| Species | Human |
| Gene ID | 140689 |
| Uniprot | Q9NTU7, |
| Species.1 | Mouse |
| Gene ID.1 | 228942 |
| Uniprot.1 | Q8BME9 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Secreted . Cell junction, synapse . Detected at GABAergic synapses. . |
| Tissue Expression | Brain, |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:May be involved in synaptic functions in the CNS. Can enable ER export and secretion of CBLN3.,similarity:Contains 1 C1q domain.,subunit:Homohexamer; disulfide-linked homotrimers. The trimers are assembled via the globular C1q domains. The trimers associate via N-terminal cysteine residues to form disulfide-linked hexamers. May interact with CBLN1, CBLN2 and CBLN3., |
