Price range: $268.00 through $328.00
Background:
The protein encoded by this gene plays important roles in the determination of centrosome position and segregation, and in the process of microtubule severing. This protein is localized to the centrosome of interphase cells, and redistributes to the region of the spindle poles during mitosis, reflecting the dynamic behavior of the centrosome during the cell cycle. [provided by RefSeq, Jan 2015],
| Size | 50μL/100μL |
| Target | CETN1 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 19kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human CETN1 AA range: 96-146 |
| Specificity | This antibody detects endogenous levels of CETN1 at Human/Mouse |
| Gene Name | CETN1 CEN1 CETN |
| Protein Name | CETN1 |
| Other Name | |
| Species | Human |
| Gene ID | 1068 |
| Uniprot | Q12798, |
| Species.1 | Mouse |
| Gene ID.1 | 26369 |
| Uniprot.1 | P41209 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cell projection, cilium . Centrosome of interphase and mitotic cells. In the retinal photoreceptor cells, localizes at the connecting cilium, a thin bridge linking the cell body and the light-sensing outer segment (By similarity). . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Plays a fundamental role in microtubule-organizing center structure and function.,miscellaneous:Binds two moles of calcium per mole of protein.,similarity:Belongs to the centrin family.,similarity:Contains 4 EF-hand domains.,subcellular location:Centrosome of interphase and mitotic cells.,subunit:Monomer., |
