CHAC1 Polyclonal Antibody
Ucallm_WP0993-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes a member of the gamma-glutamylcyclotransferase family of proteins. The encoded protein has been shown to promote neuronal differentiation by deglycination of the Notch receptor, which prevents receptor maturation and inhibits Notch signaling. This protein may also play a role in the unfolded protein response, and in regulation of glutathione levels and oxidative balance in the cell. Elevated expression of this gene may indicate increased risk of cancer recurrence among breast and ovarian cancer patients. [provided by RefSeq, Sep 2016],
Specifications
| Size | 50μL/100μL |
| Target | CHAC1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 24kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | CHAC1 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | CHAC1 BOTCH |
| Protein Name | Cation transport regulator-like protein 1 (Blocks Notch protein) (Botch) |
| Other Name | |
| Species | Human |
| Gene ID | 79094 |
| Uniprot | Q9BUX1, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q8R3J5, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | B3STU3 |
| Cellular Localization | Cytoplasm, cytosol . Golgi apparatus, trans-Golgi network . |
| Tissue Expression | Liver,Muscle, |
| Signaling_pathway | |
| Research Areas | >>Glutathione metabolism; / >>Metabolic pathways |
| Function | similarity:Belongs to the chaC family., |
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