Price range: $268.00 through $328.00
Background:
The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | CHD1 |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 188kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 960-1040 |
| Specificity | CHD1 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | CHD1 |
| Protein Name | Chromodomain-helicase-DNA-binding protein 1 (CHD-1) (ATP-dependent helicase CHD1) |
| Other Name | |
| Species | Human |
| Gene ID | 1105 |
| Uniprot | O14646, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P40201 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . Cytoplasm . Is released into the cytoplasm when cells enter mitosis and is reincorporated into chromatin during telophase-cytokinesis. . |
| Tissue Expression | Expressed in many tissues including in the brain, where the highest level of expression is found in the cerebellum and basal ganglia. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Sequence-selective DNA-binding protein. Could play an important role in gene regulation.,similarity:Belongs to the SNF2/RAD54 helicase family.,similarity:Contains 1 helicase ATP-binding domain.,similarity:Contains 1 helicase C-terminal domain.,similarity:Contains 2 chromo domains., |
