CHD6 Polyclonal Antibody
Ucallm_WP1018-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes a member of the SNF2/RAD54 helicase protein family. The encoded protein contains two chromodomains, a helicase domain, and an ATPase domain. Several multi-subunit protein complexes remodel chromatin to allow patterns of cell type-specific gene expression, and the encoded protein is thought to be a core member of one or more of these chromatin remodeling complexes. The encoded protein may function as a transcriptional repressor and is involved in the cellular repression of influenza virus replication. [provided by RefSeq, Jul 2013],
Specifications
| Size | 50μL/100μL |
| Target | CHD6 |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC, IF |
| MW(Calculated) | |
| MW(Observed) | 298kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:50-300; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | CHD6 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | CHD6 CHD5 KIAA1335 RIGB |
| Protein Name | Chromodomain-helicase-DNA-binding protein 6 (CHD-6) (ATP-dependent helicase CHD6) (Radiation-induced gene B protein) |
| Other Name | |
| Species | Human |
| Gene ID | 84181 |
| Uniprot | Q8TD26 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus, nucleoplasm . Enriched at sites of mRNA synthesis (PubMed:17027977). During influenza A virus infection, localizes to inactive chromatin. . |
| Tissue Expression | Widely expressed. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Probable transcription regulator.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence Caution:The sequence differs from position 1528 onward for unknown reasons.,similarity:Belongs to the SNF2/RAD54 helicase family.,similarity:Contains 1 helicase ATP-binding domain.,similarity:Contains 1 helicase C-terminal domain.,similarity:Contains 2 chromo domains.,tissue specificity:Ubiquitous., |
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