Product details
Background:
CHP3 rabbit pAb
Ucallm_WP16689-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | CHP3 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 24kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human CHP3 AA range: 20-70 |
| Specificity | This antibody detects endogenous levels of CHP3 at Human/Mouse |
| Gene Name | TESC CHP3 |
| Protein Name | CHP3 |
| Other Name | |
| Species | Human |
| Gene ID | 54997 |
| Uniprot | Q96BS2, |
| Species.1 | Mouse |
| Gene ID.1 | 57816 |
| Uniprot.1 | Q9JKL5 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . Cytoplasm . Membrane; Lipid-anchor . Cell membrane . Cell projection, lamellipodium . Cell projection, ruffle membrane . Colocalizes with SLC9A1 at the plasma membrane. . |
| Tissue Expression | Expressed in mature megakaryocytes and polymorphonuclear granulocytes (at protein level). Abundantly expressed in heart. Also expressed at a lower level in adult testis and salivary gland, and in the placenta. |
| Signaling_pathway | |
| Research Areas | |
| Function | Caution:It is uncertain whether Met-1 or Met-54 is the initiator.,cofactor:Binds calcium.,developmental stage:Strongly up-regulated in K562 cells treated by PMA to promote megakaryocytic differentiation, but not when treated by DMSO to promote granulocytic differentiation or by hemin to promote erythroid differentiation (at protein level).,Function:Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation.,similarity:Contains 1 EF-hand domain.,subunit:Interacts with Sodium/hydrogen exchanger 1 (SLC9A1).,tissue specificity:Abundantly expressed in heart., |
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