Name: U-Blot® Chromogranin A Rabbit mAb
SKU: WR4034
Price: 268 USD
Availability: InStock

U-Blot® Chromogranin A Rabbit mAb

WR4034 Mouse pancreas

Immunohistochemical analysis of paraffin-embedded Rat pancreas tissue. 1, primary Antibody was diluted at 1:200(4～C,overnight). 2, EDTA pH 9.0 was used for antibody retrieval(>98～C,20min). 3,Secondary antibody was diluted at 1:200(room tempeRature, 30min).

WR4034 Immunohistochemical analysis of paraffin-embedded Rat pancreas tissue. 1, primary Antibody was diluted at 1:200(4～C,overnight). 2, EDTA pH 9.0 was used for antibody retrieval(>98～C,20min). 3,Secondary antibody was diluted at 1:200(room tempeRature, 30min).

Immunohistochemical analysis of paraffin-embedded Mouse pancreas tissue. 1, primary Antibody was diluted at 1:200(4～C,overnight). 2, EDTA pH 9.0 was used for antibody retrieval(>98～C,20min). 3,Secondary antibody was diluted at 1:200(room tempeRature, 30min).

WR4034 Immunohistochemical analysis of paraffin-embedded Mouse pancreas tissue. 1, primary Antibody was diluted at 1:200(4～C,overnight). 2, EDTA pH 9.0 was used for antibody retrieval(>98～C,20min). 3,Secondary antibody was diluted at 1:200(room tempeRature, 30min).

Immunohistochemical analysis of paraffin-embedded Human pancreas tissue. 1, primary Antibody was diluted at 1:200(4～C,overnight). 2, EDTA pH 9.0 was used for antibody retrieval(>98～C,20min). 3,Secondary antibody was diluted at 1:200(room tempeRature, 30min).

WR4034 Immunohistochemical analysis of paraffin-embedded Human pancreas tissue. 1, primary Antibody was diluted at 1:200(4～C,overnight). 2, EDTA pH 9.0 was used for antibody retrieval(>98～C,20min). 3,Secondary antibody was diluted at 1:200(room tempeRature, 30min).

Price range: $268.00 through $328.00

Size

100μl

50μl

Clear

SKU: WR4034-50

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Product details

Background:The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Two other peptides, catestatin and chromofungin, have antimicrobial activity and antifungal activity, respectively. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014],

Specifications

Size	50μL/100μL
Target	Chromogranin A
Reactivity	Human, Mouse, Rat
Applications	WB, IHC, IF, IP, ELISA
MW(Calculated)	51kD
MW(Observed)	80kD
Host Species	Rabbit
Isotype	IgG,Kappa
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	IHC 1:200-1:1000; WB 1:1000-1:5000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200, / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation	PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Purification	Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
Clonality	Monoclonal
Clone Number	RM0092R
Immunogen	The specific immunogen used to produce this antibody is proprietary information.
Specificity	Endogenous
Gene Name	CHGA
Protein Name	beta Granin; betagranin (N-terminal fragment of chromogranin A); catestatin; CgA; CHG A; Chga; chromofungin; Chromogranin A; Chromogranin A parathyroid secretory protein 1; Chromogranin A precursor; ChromograninA; CMGA_HUMAN; ER-37; Pancreastatin; Parastatin; Parathyroid secretory protein 1; Pituitary secretory protein I; Secretory protein I; SP I; SP-I; SP1; SPI; vasostatin 2; Vasostatin; Vasostatin I; Vasostatin II; vasostatin-2
Other Name	beta Granin; / betagranin; / N-terminal fragment of chromogranin A; / catestatin; / CgA; / CHG A; / Chga; / chromofungin; / Chromogranin A; / Chromogranin A parathyroid secretory protein 1; / Chromogranin A precursor; / ChromograninA; / CMGA_HUMAN; / ER-37; / Pancreastatin; / Parastatin; / Parathyroid secretory protein 1; / Pituitary secretory protein I; / Secretory protein I; / SP I; / SP-I; / SP1; / SPI; / vasostatin 2; / Vasostatin; / Vasostatin I; / Vasostatin II; / vasostatin-2
Species	Human
Gene ID	1113
Uniprot	P10645,
Species.1	Mouse
Gene ID.1	12652
Uniprot.1	P26339,
Species.2	Rat
Gene ID.2
Uniprot.2	P10354
Cellular Localization	Secreted
Tissue Expression	Pancreas/ stomach
Signaling_pathway
Research Areas
Function	Function:Pancreastatin strongly inhibits glucose induced insulin release from the pancreas.,miscellaneous:Binds calcium with a low-affinity.,PTM:Sulfated on tyrosine residues and/or contains sulfated glycans.,similarity:Belongs to the chromogranin/secretogranin protein family.,subcellular location:Neuroendocrine and endocrine secretory granules.,