Price range: $268.00 through $328.00
Background:
CDC28 protein kinase regulatory subunit 2(CKS2) Homo sapiens CKS2 protein binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. The CKS2 mRNA is found to be expressed in different patterns through the cell cycle in HeLa cells, which reflects specialized role for the encoded protein. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | CKS2 |
| Reactivity | Human, Mouse |
| Applications | IHC, IF, ELISA |
| MW(Calculated) | 10kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CKS2. AA range:1-50 |
| Specificity | Cks2 Polyclonal Antibody detects endogenous levels of Cks2 protein. |
| Gene Name | CKS2 |
| Protein Name | Cyclin-dependent kinases regulatory subunit 2 |
| Other Name | CKS2; / Cyclin-dependent kinases regulatory subunit 2; / CKS-2 |
| Species | Human |
| Gene ID | 1164 |
| Uniprot | P33552, |
| Species.1 | Mouse |
| Gene ID.1 | 66197 |
| Uniprot.1 | P56390 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | cyclin-dependent protein kinase holoenzyme complex,SCF ubiquitin ligase complex, |
| Tissue Expression | Lung, |
| Signaling_pathway | Human Diseases >> Cancer: overview >> Pathways in cancer;Human Diseases >> Cancer: specific types >> Small cell lung cancer |
| Research Areas | >>Pathways in cancer; / >>Small cell lung cancer |
| Function | Function:Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.,similarity:Belongs to the CKS family.,subunit:Forms an homohexamer that can probably bind six kinase subunits., |
