CLC10 Polyclonal Antibody
Ucallm_WP2323-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell surface antigen. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | CLC10 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 34kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; IF 1:100-300; ELISA 1:5000-20000; Not yet tested in other applications. |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein AA range: 191-240 |
| Specificity | CLC10 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | CLEC10A CLECSF13 CLECSF14 HML |
| Protein Name | C-type lectin domain family 10 member A (C-type lectin superfamily member 14) (Macrophage lectin 2) (CD antigen CD301) |
| Other Name | |
| Species | Human |
| Gene ID | 10462 |
| Uniprot | Q8IUN9, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P49300, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | P49301 |
| Cellular Localization | Membrane; Single-pass type II membrane protein . |
| Tissue Expression | Brain,Peripheral blood monocyte,Testis, |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Probable role in regulating adaptive and innate immune responses. Binds in a calcium-dependent manner to terminal galactose and N-acetylgalactosamine units, linked to serine or threonine. These sugar moieties are known as Tn-Ag and are expressed in a variety of carcinoma cells.,online information:MGL,similarity:Contains 1 C-type lectin domain., |
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