function:Seems to act as a chloride ion channel., similarity:Belongs to the chloride channel MCLC family.,
Specifications
Size
50μL/100μL
Target
CLCC1
Reactivity
Human, Mouse, Rat
Applications
WB, IF, ELISA
MW(Calculated)
MW(Observed)
62kD
Host Species
Rabbit
Isotype
IgG
Conjugate/Modification
Unmodified
Recommended Dilution Ratio
WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:40000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
The antiserum was produced against synthesized peptide derived from human CLCC1. AA range:391-440
Specificity
CLCC1 Polyclonal Antibody detects endogenous levels of CLCC1 protein.
Gene Name
CLCC1
Protein Name
Chloride channel CLIC-like protein 1
Other Name
CLCC1; / KIAA0761; / MCLC; / Chloride channel CLIC-like protein 1; / Mid-1-related chloride channel protein 1
Species
Human
Gene ID
23155
Uniprot
Q96S66,
Species.1
Mouse
Gene ID.1
Uniprot.1
Q99LI2
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Endoplasmic reticulum membrane; Multi-pass membrane protein . Golgi apparatus membrane; Multi-pass membrane protein . Nucleus membrane; Multi-pass membrane protein . Within the endoplasmic reticulum (ER), localizes to the mitochondria-associated ER membrane, a zone of contact between the ER and mitochondrial membranes. .
Tissue Expression
Expressed in the retina of the eye, with extensive expression in the lamina cribrosa, optic nerve, ganglion cell layer, inner nuclear layer, outer nuclear layer and retinal pigment epithelium.
Signaling_pathway
Research Areas
Function
Function:Seems to act as a chloride ion channel.,similarity:Belongs to the chloride channel MCLC family.,