CLLD7 Polyclonal Antibody
Ucallm_WP11680-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes a protein with an N-terminal RCC1 domain and a C-terminal BTB (broad complex, tramtrack and bric-a-brac) domain. In rat, over-expression of this gene in vascular smooth muscle cells induced cellular hypertrophy. In rat, the C-terminus of RCBTB1 interacts with the angiotensin II receptor-1A. In humans, this gene maps to a region of chromosome 13q that is frequently deleted in B-cell chronic lymphocytic leukemia and other lymphoid malignancies. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | CLLD7 |
| Reactivity | Human, Mouse |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 58kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human RCBTB1. AA range:251-300 |
| Specificity | CLLD7 Polyclonal Antibody detects endogenous levels of CLLD7 protein. |
| Gene Name | RCBTB1 |
| Protein Name | RCC1 and BTB domain-containing protein 1 |
| Other Name | RCBTB1; / CLLD7; / E4.5; / RCC1 and BTB domain-containing protein 1; / Chronic lymphocytic leukemia deletion region gene 7 protein; / CLL deletion region gene 7 protein; / Regulator of chromosome condensation and BTB domain-containing protein 1 |
| Species | Human |
| Gene ID | 55213 |
| Uniprot | Q8NDN9, |
| Species.1 | Mouse |
| Gene ID.1 | 71330 |
| Uniprot.1 | Q6NXM2 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . |
| Tissue Expression | Ubiquitously expressed (PubMed:11306461, PubMed:27486781). In the retina, present in the nerve fiber layer and to a lesser extent in the inner and outer plexiform layers (at protein level) (PubMed:27486781). |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:May be involved in cell cycle regulation by chromatin remodeling.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 2 BTB (POZ) domains.,similarity:Contains 6 RCC1 repeats.,tissue specificity:Ubiquitously expressed., |
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