SKU: WP15710 Categories: ,

CMTM8 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP15710-100
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Product details

Background:

This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. This gene acts as a tumor suppressor, and plays a role in regulating the migration of tumor cells. The encoded protein is thought to function as a a negative regulator of epidermal growth factor-induced signaling. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016],

Specifications

Size50μL/100μL
TargetCMTM8
ReactivityHuman, Mouse
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)20kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IHC: 1:100-1:300; ELISA 1:10000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human CMTM8. AA range:101-150
SpecificityCMTM8 Polyclonal Antibody detects endogenous levels of CMTM8 protein.
Gene NameCMTM8
Protein NameCKLF-like MARVEL transmembrane domain-containing protein 8
Other NameCMTM8; / CKLFSF8; / CKLF-like MARVEL transmembrane domain-containing protein 8; / Chemokine-like factor superfamily member 8
SpeciesHuman
Gene ID152189
UniprotQ8IZV2,
Species.1Mouse
Gene ID.170031
Uniprot.1Q9CZR4
Species.2
Gene ID.2
Uniprot.2
Cellular Localization[Isoform 1]: Membrane; Multi-pass membrane protein.; [Isoform 2]: Cytoplasm. Nucleus.
Tissue ExpressionHighly expressed in liver and pancreas.
Signaling_pathway
Research Areas
Functionsimilarity:Belongs to the chemokine-like factor family.,similarity:Contains 1 MARVEL domain.,tissue specificity:Highly expressed in liver and pancreas.,
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