Price range: $268.00 through $328.00
Background:
COX19 encodes a cytochrome c oxidase (COX)-assembly protein. The S. cerevisiae Cox19 protein may play a role in metal transport to the mitochondrial intermembrane space and assembly of complex IV of the mitochondrial respiratory chain (Sacconi et al., 2005 [PubMed 16212937]).[supplied by OMIM, Mar 2008],
| Size | 50μL/100μL |
| Target | COX19 |
| Reactivity | Human, Mouse |
| Applications | IHC, IF, ELISA |
| MW(Calculated) | 10kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human COX19. AA range:10-59 |
| Specificity | COX19 Polyclonal Antibody detects endogenous levels of COX19 protein. |
| Gene Name | COX19 |
| Protein Name | Cytochrome c oxidase assembly protein COX19 |
| Other Name | COX19; / Cytochrome c oxidase assembly protein COX19; / hCOX19 |
| Species | Human |
| Gene ID | 90639 |
| Uniprot | Q49B96, |
| Species.1 | Mouse |
| Gene ID.1 | 68033 |
| Uniprot.1 | Q8K0C8 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm, cytosol . Mitochondrion intermembrane space . Mitochondrion . Partitions between mitochondria and the cytosol in a copper-dependent manner. Enriched in the cytosol when intracellular copper concentrations are elevated. . |
| Tissue Expression | Ubiquitously expressed. Highly expressed in skeletal muscle. |
| Signaling_pathway | |
| Research Areas | >>Thermogenesis |
| Function | Function:May be required for the assembly of mitochondrial cytochrome c oxidase.,similarity:Belongs to the COX19 family.,similarity:Contains 1 CHCH domain.,tissue specificity:Ubiquitously expressed. Highly expressed in skeletal muscle., |
