Price range: $268.00 through $328.00
Background:
retinol binding protein 5(RBP5) Homo sapiens The protein encoded by this gene is a cellular retinol-binding protein expressed highly in kidney and liver. Down-regulation of the encoded protein in hepatocellular carcinoma was associated with large tumor size and poor patient survival rates. [provided by RefSeq, Jul 2016],
| Size | 50μL/100μL |
| Target | CRBP-III |
| Reactivity | Human |
| Applications | IHC, IF, ELISA |
| MW(Calculated) | 16kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CRBP III. AA range:10-59 |
| Specificity | CRBP-III Polyclonal Antibody detects endogenous levels of CRBP-III protein. |
| Gene Name | RBP5 |
| Protein Name | Retinol-binding protein 5 |
| Other Name | RBP5; / Retinol-binding protein 5; / Cellular retinol-binding protein III; / CRBP-III; / HRBPiso |
| Species | Human |
| Gene ID | 83758 |
| Uniprot | P82980 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm . |
| Tissue Expression | Higher expression in adult kidney and liver and to a lesser extent in adult and fetal spleen, adult lymph nodes and appendix, and fetal liver and kidney. Strongly decreased in hepatocellular carcinoma tissues (at protein level). |
| Signaling_pathway | |
| Research Areas | |
| Function | Domain:Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.,Function:Intracellular transport of retinol.,similarity:Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.,tissue specificity:Higher expression in adult kidney and liver and to a lesser extent in adult and fetal spleen, adult lymph nodes and appendix, and fetal liver and kidney. Strongly decreased in hepatocellular carcinoma tissues (at protein level)., |
