Name: Creatine Kinase M Polyclonal Antibody
SKU: WP11791
Price: 268 USD
Availability: InStock

Creatine Kinase M Polyclonal Antibody

Ucallm_WP11791-50

Price range: $268.00 through $328.00

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50μl

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SKU: WP11791-100

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Product details

Background:

The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. [provided by RefSeq, Jul 2008],

Specifications

Size	50μL/100μL
Target	CK-MM
Reactivity	Human, Mouse, Rat
Applications	WB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)	43kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:40000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	The antiserum was produced against synthesized peptide derived from human M-CK. AA range:10-59
Specificity	Creatine Kinase M Polyclonal Antibody detects endogenous levels of Creatine Kinase M protein.
Gene Name	CKM
Protein Name	Creatine kinase M-type
Other Name	CKM; / CKMM; / Creatine kinase M-type; / Creatine kinase M chain; / M-CK
Species	Human
Gene ID	1158
Uniprot	P06732,
Species.1	Mouse
Gene ID.1	12715
Uniprot.1	P07310,
Species.2	Rat
Gene ID.2	24265
Uniprot.2	P00564
Cellular Localization	Cytoplasm.
Tissue Expression	Liver,
Signaling_pathway
Research Areas	>>Arginine and proline metabolism; / >>Metabolic pathways
Function	Catalytic activity:ATP + creatine = ADP + phosphocreatine.,Function:Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.,online information:CKM entry,online information:Creatine kinase entry,similarity:Belongs to the ATP:guanido phosphotransferase family.,subunit:Dimer of identical or non-identical chains. With MM being the major form in skeletal muscle and myocardium, MB existing in myocardium, and BB existing in many tissues, especially brain.,

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Creatine Kinase M Polyclonal Antibody

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Creatine Kinase M Polyclonal Antibody

Product details

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