DB123 rabbit pAb
Ucallm_WP4023-50
Price range: $268.00 through $328.00
Product details
Background:
Defensins are cysteine-rich cationic polypeptides that are important in the host immunologic response to invading microorganisms. This antimicrobial protein is secreted and is a member of the beta defensin protein family. Beta defensin genes are found in several clusters throughout the genome, with this gene mapping to a cluster at 20q11.1. Two transcript variants, one protein-coding and the other not, have been found for this gene. [provided by RefSeq, Nov 2014],
Specifications
| Size | 50μL/100μL |
| Target | DB123 |
| Reactivity | Human |
| Applications | IHC, IF |
| MW(Calculated) | 7kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:50-200; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human DB123 AA range: 1-51 |
| Specificity | This antibody detects endogenous levels of DB123 at Human |
| Gene Name | DEFB123 DEFB23 UNQ1963/PRO4485 |
| Protein Name | DB123 |
| Other Name | |
| Species | Human |
| Gene ID | 245936 |
| Uniprot | Q8N688 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Secreted . |
| Tissue Expression | Abundant expression in the male reproductive tract only. Abundant expressed in testis and the caput region of epididymis, but low in the corpus region. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Has antibacterial activity .,similarity:Belongs to the beta-defensin family., |
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