DHHC-9 Polyclonal Antibody
Ucallm_WP12006-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes an integral membrane protein that is a member of the zinc finger DHHC domain-containing protein family. The encoded protein forms a complex with golgin subfamily A member 7 and functions as a palmitoyltransferase. This protein specifically palmitoylates HRAS and NRAS. Mutations in this gene are associated with X-linked mental retardation. Alternate splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq, May 2010],
Specifications
| Size | 50μL/100μL |
| Target | DHHC-9 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 41kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ZDHHC9. AA range:315-364 |
| Specificity | DHHC-9 Polyclonal Antibody detects endogenous levels of DHHC-9 protein. |
| Gene Name | ZDHHC9 |
| Protein Name | Palmitoyltransferase ZDHHC9 |
| Other Name | ZDHHC9; / CXorf11; / ZDHHC10; / ZNF379; / ZNF380; / CGI-89; / Palmitoyltransferase ZDHHC9; / Zinc finger DHHC domain-containing protein 9; / DHHC-9; / DHHC9; / Zinc finger protein 379; / Zinc finger protein 380 |
| Species | Human |
| Gene ID | 51114 |
| Uniprot | Q9Y397, |
| Species.1 | Mouse |
| Gene ID.1 | 208884 |
| Uniprot.1 | P59268 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Endoplasmic reticulum membrane; Multi-pass membrane protein . Golgi apparatus membrane; Multi-pass membrane protein . |
| Tissue Expression | Highly expressed in kidney, skeletal muscle, brain, lung and liver. Absent in thymus, spleen and leukocytes. |
| Signaling_pathway | |
| Research Areas | |
| Function | Catalytic activity:Palmitoyl-CoA + protein-cysteine = S-palmitoyl protein + CoA.,Domain:The DHHC domain is required for palmitoyltransferase activity.,Function:The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS.,similarity:Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.,similarity:Contains 1 DHHC-type zinc finger.,subunit:Interacts with GOLGA7.,tissue specificity:Highly expressed in kidney, skeletal muscle, brain, lung and liver. Absent in thymus, spleen and leukocytes., |
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