This gene consists of two exons and encodes a 104aa protein. Disruption of this gene by translocation t(2;3)(q33;q21) is associated with familial clear cell renal cancer. [provided by RefSeq, Sep 2010],
Specifications
Size
50μL/100μL
Target
DIRC1
Reactivity
Human
Applications
WB, ELISA
MW(Calculated)
MW(Observed)
11kD
Host Species
Rabbit
Isotype
IgG
Conjugate/Modification
Unmodified
Recommended Dilution Ratio
WB 1:500-2000; ELISA 1:5000-20000
Formulation
Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human protein . at AA range: 20-100
Specificity
DIRC1 Polyclonal Antibody detects endogenous levels of protein.
Gene Name
DIRC1
Protein Name
Disrupted in renal carcinoma protein 1 (Disrupted in renal cancer protein)
Other Name
Species
Human
Gene ID
116093
Uniprot
Q969H9
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Tissue Expression
Expressed at low steady-state level in adult placenta, testis, ovary, prostate, fetal kidney, spleen and skeletal muscle.
Signaling_pathway
Research Areas
Function
Disease:A chromosomal aberration involving DIRC1 is found in familial renal cell carcinoma 1-related translocation t(2; 3)(q33; q21) (RCC1).,tissue specificity:Expressed at low steady-state level in adult placenta, testis, ovary, prostate, fetal kidney, spleen and skeletal muscle.,