SKU: WP6825 Categories: ,

DNALI1 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP6825-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetDNALI1
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)28kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human DNALI1
SpecificityThis antibody detects endogenous levels of DNALI1 at Human, Mouse,Rat
Gene NameDNALI1
Protein NameAxonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal) (hp28)
Other Name
SpeciesHuman
Gene ID7802
UniprotO14645,
Species.1Mouse
Gene ID.175563
Uniprot.1Q8BVN8,
Species.2Rat
Gene ID.2298524
Uniprot.2Q4FZV3
Cellular LocalizationCell projection, cilium . Cell projection, cilium, flagellum . Dynein axonemal particle . Cytoplasm .
Tissue ExpressionExpressed in many tissues. A smaller 0.9 kb and a larger 2.5 kb transcripts were detected at the highest level in the testis, at medium levels in the prostate, heart, liver, lung and pancreas, at low levels in the ovary, skeletal muscle and small intestine. Not detected in spleen, colon epithelium, thymus or peripheral blood leukocytes. The 0.9 kb transcript is expressed at a 20-fold higher level than the 2.5 kb transcript in the testis. Expressed in spermatozoa and airway epithelial cells (at protein level) (PubMed:31178125).
Signaling_pathwayHuman Diseases >> Neurodegenerative disease >> Amyotrophic lateral sclerosis;Human Diseases >> Neurodegenerative disease >> Huntington disease;Human Diseases >> Neurodegenerative disease >> Pathways of neurodegeneration - multiple diseases
Research Areas
FunctionMay play a dynamic role in flagellar motility.
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