DNJC2 Polyclonal Antibody
Ucallm_WP3215-50
Price range: $268.00 through $328.00
Product details
Background:
This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | DNAJC2 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 68kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein AA range: 406-456 |
| Specificity | DNJC2 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | DNAJC2 MPHOSPH11 MPP11 ZRF1 |
| Protein Name | DnaJ homolog subfamily C member 2 |
| Other Name | DnaJ homolog subfamily C member 2; / M-phase phosphoprotein 11; / Zuotin-related factor 1 |
| Species | Human |
| Gene ID | 27000 |
| Uniprot | Q99543, |
| Species.1 | Mouse |
| Gene ID.1 | 22791 |
| Uniprot.1 | P54103, |
| Species.2 | Rat |
| Gene ID.2 | 116456 |
| Uniprot.2 | Q7TQ20 |
| Cellular Localization | Nucleus . Cytoplasm, cytosol . |
| Tissue Expression | Widely expressed. |
| Signaling_pathway | |
| Research Areas | |
| Function | PTM:Phosphorylated in M (mitotic) phase.,similarity:Contains 1 J domain.,similarity:Contains 2 SANT domains., |
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