Price range: $268.00 through $328.00
Background:
This gene encodes a member of the CRMP (collapsing response mediator protein) family thought to be involved in neural development. Antibodies to the encoded protein were found in some patients with neurologic symptoms who had paraneoplastic syndrome. A pseudogene of this gene is found on chromosome 11. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011],
| Size | 50μL/100μL |
| Target | DPYL5 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | |
| MW(Observed) | 60kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human DPYL5 AA range: 396-446 |
| Specificity | This antibody detects endogenous levels of DPYL5 at Human/Mouse/Rat |
| Gene Name | DPYSL5 CRMP5 ULIP6 |
| Protein Name | DPYL5 |
| Other Name | Dihydropyrimidinase-related protein 5; / DRP-5; / CRMP3-associated molecule; / CRAM; / Collapsin response mediator protein 5; / CRMP-5; / UNC33-like phosphoprotein 6; / ULIP-6 |
| Species | Human |
| Gene ID | 56896 |
| Uniprot | Q9BPU6, |
| Species.1 | Mouse |
| Gene ID.1 | 65254 |
| Uniprot.1 | Q9EQF6, |
| Species.2 | Rat |
| Gene ID.2 | 100910964 |
| Uniprot.2 | Q9JHU0 |
| Cellular Localization | Cytoplasm . |
| Tissue Expression | Amygdala,Brain,Cajal-Retzius cell,Fetal brain cortex,Lung,Spinal cord, |
| Signaling_pathway | |
| Research Areas | >>Axon guidance |
| Function | Function:May have a function in neuronal differentiation and/or axon growth.,similarity:Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.,subunit:Homotetramer, and heterotetramer with other DPYS-like proteins. Interacts with DPYSL2, DPYSL3 and DPYSL4., |
