Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human DRAP1
Specificity
This antibody detects endogenous levels of DRAP1 at Human, Mouse,Rat
Gene Name
DRAP1
Protein Name
Dr1-associated corepressor (Dr1-associated protein 1) (Negative co-factor 2-alpha) (NC2-alpha)
Other Name
Species
Human
Gene ID
10589
Uniprot
Q14919,
Species.1
Mouse
Gene ID.1
66556
Uniprot.1
Q9D6N5,
Species.2
Rat
Gene ID.2
293674
Uniprot.2
A0JPP1
Cellular Localization
Nucleus .
Tissue Expression
Ubiquitous. Highly expressed in adult testis, heart, skeletal muscle, pancreas and brain, and in fetal brain, liver and kidney.
Signaling_pathway
Research Areas
Function
The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own.