SKU: WP3652 Categories: ,

DRP2 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP3652-100
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Product details

Background:

Members of the dystrophin family of proteins perform a critical role in the maintenance of membrane-associated complexes at points of intercellular contact in vertebrate cells. The protein encoded by this gene is predicted to resemble certain short C-terminal isoforms of dystrophin and dystrophin-related protein 1 (DRP1 or utrophin). DRP2 is expressed principally in the brain and spinal cord. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010],

Specifications

Size50μL/100μL
TargetDRP2
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)
MW(Observed)105kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human DRP2 AA range: 437-487
SpecificityThis antibody detects endogenous levels of DRP2 at Human/Mouse/Rat
Gene NameDRP2
Protein NameDRP2
Other NameDystrophin-related protein 2; / DRP-2
SpeciesHuman
Gene ID1821
UniprotQ13474,
Species.1Mouse
Gene ID.113497
Uniprot.1Q05AA6,
Species.2Rat
Gene ID.266027
Uniprot.2Q9EPA0
Cellular LocalizationCell junction, synapse, postsynaptic density . Cell projection, dendrite . Perikaryon . Cell membrane; Peripheral membrane protein . Detected in Schwann cells at periaxonal myelin membranes. .
Tissue ExpressionDetected in fetal brain.
Signaling_pathway
Research Areas
FunctionFunction:Possibly involved in membrane-cytoskeleton interactions of the central nervous system.,similarity:Contains 1 WW domain.,similarity:Contains 1 ZZ-type zinc finger.,similarity:Contains 2 spectrin repeats.,tissue specificity:Brain and spinal cord; very low levels in eye, ovary, epididymis and testis; not in cardiac and skeletal muscle.,
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