DRP2 rabbit pAb
Ucallm_WP3652-50
Price range: $268.00 through $328.00
Product details
Background:
Members of the dystrophin family of proteins perform a critical role in the maintenance of membrane-associated complexes at points of intercellular contact in vertebrate cells. The protein encoded by this gene is predicted to resemble certain short C-terminal isoforms of dystrophin and dystrophin-related protein 1 (DRP1 or utrophin). DRP2 is expressed principally in the brain and spinal cord. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010],
Specifications
| Size | 50μL/100μL |
| Target | DRP2 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | |
| MW(Observed) | 105kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human DRP2 AA range: 437-487 |
| Specificity | This antibody detects endogenous levels of DRP2 at Human/Mouse/Rat |
| Gene Name | DRP2 |
| Protein Name | DRP2 |
| Other Name | Dystrophin-related protein 2; / DRP-2 |
| Species | Human |
| Gene ID | 1821 |
| Uniprot | Q13474, |
| Species.1 | Mouse |
| Gene ID.1 | 13497 |
| Uniprot.1 | Q05AA6, |
| Species.2 | Rat |
| Gene ID.2 | 66027 |
| Uniprot.2 | Q9EPA0 |
| Cellular Localization | Cell junction, synapse, postsynaptic density . Cell projection, dendrite . Perikaryon . Cell membrane; Peripheral membrane protein . Detected in Schwann cells at periaxonal myelin membranes. . |
| Tissue Expression | Detected in fetal brain. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Possibly involved in membrane-cytoskeleton interactions of the central nervous system.,similarity:Contains 1 WW domain.,similarity:Contains 1 ZZ-type zinc finger.,similarity:Contains 2 spectrin repeats.,tissue specificity:Brain and spinal cord; very low levels in eye, ovary, epididymis and testis; not in cardiac and skeletal muscle., |
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