Product details
Background:
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DTNB rabbit pAb
Ucallm_WP8195-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | DTNB |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 69kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human DTNB |
| Specificity | This antibody detects endogenous levels of DTNB at Human, Mouse,Rat |
| Gene Name | DTNB |
| Protein Name | Dystrobrevin beta (DTN-B) (Beta-dystrobrevin) |
| Other Name | |
| Species | Human |
| Gene ID | 1838 |
| Uniprot | O60941, |
| Species.1 | Mouse |
| Gene ID.1 | 13528 |
| Uniprot.1 | O70585, |
| Species.2 | Rat |
| Gene ID.2 | 362715 |
| Uniprot.2 | P84060 |
| Cellular Localization | Cytoplasm . Cell junction, synapse, postsynaptic density . Cell projection, dendrite . Basal cell membrane . Cell junction, synapse, postsynapse . Nucleus . Localized at inhibitory synapses on the dendrites of cerebellar Purkinje cells. . |
| Tissue Expression | Highly expressed in brain, kidney and pancreas. |
| Signaling_pathway | |
| Research Areas | |
| Function | Scaffolding protein that assembles DMD and SNTA1 molecules to the basal membrane of kidney cells and liver sinusoids (By similarity). May function as a repressor of the SYN1 promoter through the binding of repressor element-1 (RE-1), in turn regulates SYN1 expression and may be involved in cell proliferation regulation during the early phase of neural differentiation . May be required for proper maturation and function of a subset of inhibitory synapses (By similarity). |
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