SKU: WP8195 Categories: ,

DTNB rabbit pAb

Price range: $268.00 through $328.00

SKU: WP8195-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetDTNB
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)69kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human DTNB
SpecificityThis antibody detects endogenous levels of DTNB at Human, Mouse,Rat
Gene NameDTNB
Protein NameDystrobrevin beta (DTN-B) (Beta-dystrobrevin)
Other Name
SpeciesHuman
Gene ID1838
UniprotO60941,
Species.1Mouse
Gene ID.113528
Uniprot.1O70585,
Species.2Rat
Gene ID.2362715
Uniprot.2P84060
Cellular LocalizationCytoplasm . Cell junction, synapse, postsynaptic density . Cell projection, dendrite . Basal cell membrane . Cell junction, synapse, postsynapse . Nucleus . Localized at inhibitory synapses on the dendrites of cerebellar Purkinje cells. .
Tissue ExpressionHighly expressed in brain, kidney and pancreas.
Signaling_pathway
Research Areas
FunctionScaffolding protein that assembles DMD and SNTA1 molecules to the basal membrane of kidney cells and liver sinusoids (By similarity). May function as a repressor of the SYN1 promoter through the binding of repressor element-1 (RE-1), in turn regulates SYN1 expression and may be involved in cell proliferation regulation during the early phase of neural differentiation . May be required for proper maturation and function of a subset of inhibitory synapses (By similarity).
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