Dyrk4 Polyclonal Antibody
Ucallm_WP12090-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes an enzyme that belongs to a conserved family of serine/threonine protein kinases. Members of this dual specificity kinase family are thought to function in the regulation of cell differentiation and proliferation, survival, and in development. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Aug 2013],
Specifications
| Size | 50μL/100μL |
| Target | Dyrk4 |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 60kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from Dyrk4 . at AA range: 350-430 |
| Specificity | Dyrk4 Polyclonal Antibody detects endogenous levels of Dyrk4 protein. |
| Gene Name | DYRK4 |
| Protein Name | Dual specificity tyrosine-phosphorylation-regulated kinase 4 |
| Other Name | DYRK4; / Dual specificity tyrosine-phosphorylation-regulated kinase 4 |
| Species | Human |
| Gene ID | 8798 |
| Uniprot | Q9NR20, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q8BI55 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | [Isoform 1]: Cytoplasm .; [Isoform 4]: Cytoplasm . Nucleus . |
| Tissue Expression | Brain,Kidney,Lung,Testis, |
| Signaling_pathway | |
| Research Areas | |
| Function | Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,Function:Possible non-essential role in spermiogenesis.,PTM:Autophosphorylated on tyrosine residues.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.,similarity:Contains 1 protein kinase domain., |
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