Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human EAPP
Specificity
This antibody detects endogenous levels of EAPP at Human, Mouse
Gene Name
EAPP C14orf11 BM-036
Protein Name
E2F-associated phosphoprotein (EAPP)
Other Name
Species
Human
Gene ID
55837
Uniprot
Q56P03,
Species.1
Mouse
Gene ID.1
66266
Uniprot.1
Q5BU09
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Cytoplasm. Nucleus.
Tissue Expression
Ubiquitously expressed. Highest levels in heart, placenta, skeletal muscle and pancreas. Lower levels in brain, lung and kidney. In the brain, expressed in all regions with high levels in the cerebellum and cerebral cortex. Expressed in COS1 and transformed skin fibroblasts.
Signaling_pathway
Research Areas
Function
May play an important role in the fine-tuning of both major E2F1 activities, the regulation of the cell-cycle and the induction of apoptosis. Promotes S-phase entry, and inhibits p14(ARP) expression.