Price range: $268.00 through $328.00
Background:
This gene encodes a translation elongation factor. The protein is a guanine nucleotide exchange factor involved in the transfer of aminoacylated tRNAs to the ribosome. Alternative splicing results in three transcript variants which differ only in the 5' UTR. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | EF-1β |
| Reactivity | Human, Mouse |
| Applications | IHC, WB, IF, ELISA |
| MW(Calculated) | 24kD |
| MW(Observed) | 30kD |
| Host Species | Mouse |
| Isotype | IgG1,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:200-1000; WB 1:500-2000; IF 1:100-500; ELISA 1:1000-5000 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein G affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RMMR2161 |
| Immunogen | Synthesized peptide derived from human EF-1beta. AA range:100-225 |
| Specificity | This antibody detects endogenous levels of EF-1β. |
| Gene Name | EEF1B2 |
| Protein Name | Elongation factor 1-beta |
| Other Name | EEF1B2; / EEF1B; / EF1B; / Elongation factor 1-beta; / EF-1-beta |
| Species | Human |
| Gene ID | 1933 |
| Uniprot | P24534, |
| Species.1 | Mouse |
| Gene ID.1 | 55949 |
| Uniprot.1 | O70251 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasmic |
| Tissue Expression | Brain,Epithelium,Eye,Fetal brain cortex,Keratinocyt |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.,PTM:Phosphorylation affects the GDP/GTP exchange rate.,similarity:Belongs to the EF-1-beta/EF-1-delta family.,similarity:Contains 1 GST C-terminal domain.,subunit:EF-1 is composed of 4 subunits: alpha, beta, delta, and gamma., |
