SKU: WP1120 Categories: ,

EFGM Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP1120-100
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Product details

Background:

Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. This gene encodes one of the mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetEFGM
ReactivityHuman, Mouse, Rat
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)82kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from part region of human protein
SpecificityEFGM Polyclonal Antibody detects endogenous levels of protein.
Gene NameGFM1 EFG EFG1 GFM
Protein NameElongation factor G, mitochondrial (EF-Gmt) (Elongation factor G 1, mitochondrial) (mEF-G 1) (Elongation factor G1) (hEFG1)
Other Name
SpeciesHuman
Gene ID85476
UniprotQ96RP9,
Species.1Mouse
Gene ID.1
Uniprot.1Q8K0D5,
Species.2Rat
Gene ID.2
Uniprot.2Q07803
Cellular LocalizationMitochondrion .
Tissue Expression
Signaling_pathway
Research Areas
Functiontranslation, translational elongation, mitochondrion organization, mitochondrial translation, mitochondrial translational elongation,
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