SKU: WP0527 Categories: ,

EFNB2 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP0527-100
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Product details

Background:

This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetEFNB2
ReactivityHuman, Mouse
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)36kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human protein . at AA range: 210-290
SpecificityEFNB2 Polyclonal Antibody detects endogenous levels of protein.
Gene NameEFNB2 EPLG5 HTKL LERK5
Protein NameEphrin-B2 (EPH-related receptor tyrosine kinase ligand 5) (LERK-5) (HTK ligand) (HTK-L)
Other Name
SpeciesHuman
Gene ID1948
UniprotP52799,
Species.1Mouse
Gene ID.1
Uniprot.1P52800
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCell membrane; Single-pass type I membrane protein . Cell junction, adherens junction .
Tissue ExpressionLung and kidney.
Signaling_pathway
Research Areas>>Axon guidance
FunctionFunction:Binds to the receptor tyrosine kinases EPHB4 and EPHA3. May play a role in constraining the orientation of longitudinally projecting axons.,PTM:Inducible phosphorylation of tyrosine residues in the cytoplasmic domain.,similarity:Belongs to the ephrin family.,subunit:Interacts with PDZRN3 (By similarity). Binds to the receptor tyrosine kinases EPHB4 and EPHA3. Binds to Nipah virus G protein.,tissue specificity:Lung and kidney.,
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