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EFNB2 Polyclonal Antibody
Ucallm_WP0527-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | EFNB2 |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 36kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 210-290 |
| Specificity | EFNB2 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | EFNB2 EPLG5 HTKL LERK5 |
| Protein Name | Ephrin-B2 (EPH-related receptor tyrosine kinase ligand 5) (LERK-5) (HTK ligand) (HTK-L) |
| Other Name | |
| Species | Human |
| Gene ID | 1948 |
| Uniprot | P52799, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P52800 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein . Cell junction, adherens junction . |
| Tissue Expression | Lung and kidney. |
| Signaling_pathway | |
| Research Areas | >>Axon guidance |
| Function | Function:Binds to the receptor tyrosine kinases EPHB4 and EPHA3. May play a role in constraining the orientation of longitudinally projecting axons.,PTM:Inducible phosphorylation of tyrosine residues in the cytoplasmic domain.,similarity:Belongs to the ephrin family.,subunit:Interacts with PDZRN3 (By similarity). Binds to the receptor tyrosine kinases EPHB4 and EPHA3. Binds to Nipah virus G protein.,tissue specificity:Lung and kidney., |
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