EGFL6 rabbit pAb
Ucallm_WP16748-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes a member of the epidermal growth factor (EGF) repeat superfamily. Members of this superfamily are characterized by the presence of EGF-like repeats and are often involved in the regulation of cell cycle, proliferation, and developmental processes. The gene product contains a signal peptide, suggesting that it is secreted; an EGF repeat region consisting of 4 complete EGF-like repeats and 1 partial EGF-like repeat, 3 of which have a calcium-binding consensus sequence; an arg-gly-asp integrin association motif; and a MAM domain, which is believed to have an adhesive function. This gene is expressed early during development, and its expression has been detected in lung and meningioma tumors. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | EGFL6 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 61kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human EGFL6 AA range: 144-194 |
| Specificity | This antibody detects endogenous levels of EGFL6 at Human/Mouse |
| Gene Name | EGFL6 MAEG PP648 UNQ281/PRO320 |
| Protein Name | EGFL6 |
| Other Name | |
| Species | Human |
| Gene ID | 25975 |
| Uniprot | Q8IUX8, |
| Species.1 | Mouse |
| Gene ID.1 | 54156 |
| Uniprot.1 | Q9JJZ5 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Secreted, extracellular space, extracellular matrix, basement membrane . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | developmental stage:Only detected in fetal tissues.,Function:May bind integrin alpha-8/beta-1 and play a role in hair follicle morphogenesis. Promotes matrix assembly.,similarity:Belongs to the nephronectin family.,similarity:Contains 1 MAM domain.,similarity:Contains 5 EGF-like domains., |
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