SKU: WP12131 Categories: ,

Egr-3 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP12131-100
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Product details

Background:

This gene encodes a transcriptional regulator that belongs to the EGR family of C2H2-type zinc-finger proteins. It is an immediate-early growth response gene which is induced by mitogenic stimulation. The protein encoded by this gene participates in the transcriptional regulation of genes in controling biological rhythm. It may also play a role in a wide variety of processes including muscle development, lymphocyte development, endothelial cell growth and migration, and neuronal development. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2010],

Specifications

Size50μL/100μL
TargetEgr-3
ReactivityHuman, Mouse, Rat
ApplicationsIHC, IF, ELISA
MW(Calculated)43kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioIHC 1:100-1:300; ELISA 1:10000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human EGR3. AA range:338-387
SpecificityEgr-3 Polyclonal Antibody detects endogenous levels of Egr-3 protein.
Gene NameEGR3
Protein NameEarly growth response protein 3
Other NameEGR3; / PILOT; / Early growth response protein 3; / EGR-3; / Zinc finger protein pilot
SpeciesHuman
Gene ID1960
UniprotQ06889,
Species.1Mouse
Gene ID.113655
Uniprot.1P43300,
Species.2Rat
Gene ID.225148
Uniprot.2P43301
Cellular LocalizationNucleus .
Tissue ExpressionBrain,Peripheral blood T-cell,
Signaling_pathway
Research Areas>>C-type lectin receptor signaling pathway; / >>Hepatitis B; / >>Viral carcinogenesis
Functiondevelopmental stage:In T-cells, expressed 20 minutes following activation.,Function:Probable transcription factor involved in muscle spindle development.,similarity:Belongs to the EGR C2H2-type zinc-finger protein family.,similarity:Contains 3 C2H2-type zinc fingers.,
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